Pharmacology Graduate Level Courses

PMCOL512PMCOL514PMCOL515 … PMCOL525 … PMCOL550 … PMCOL575 … PMCOL612



PMCOL 512
Pharmacology of the Synapse
Fall term every other year, T R 14:00
Coordinator: Dr PA Smith

Prerequisites: Consent of the Department

Grading: Grading is based on a brief midterm exam and on 2 oral reports and 2 term papers

This graduate course gets right down to the nuts and bolts of how drugs affect nerve cells. The emphasis is on electrophysiology and imaging techniques. Much of the course involves evaluation of contemporary scientific literature and thus provides an ideal background for graduate students in pharmacology, physiology and neuroscience.

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PMCOL 514
Biophysical Aspects of Ion Channel Pharmacology
Winter term every other year, T R 09:30
Coordinator: Dr PE Light

Prerequisites: Consent of Department

Grading: TBA

A comprehensive examination of ion channels and their pharmacology. Topics to be covered include: molecular pharmacology, fundamental principles of bioelectricity, ion channel recording, analysis, classification, moledular biology, structure, pathophysiology and hereditary disease.

Prerequisites:  Consent of Department.

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PMCOL 515
Cardiovascular Pharmacology
Fall term, M W F 11:00
Coordinator: Dr R Schulz

Prerequisites: Consent of the Department

Grading: TBA

Critical discussion and analysis of current research papers in cardiovascular pharmacology, grouped into themes. Recent developments and use of the literature will be emphasized. In-class participation during roundtable discussion to critique assigned papers is essential. Each theme will be accompanied by the student's written analyses of papers assigned but not discussed in class, in the format of a condensation/critique.

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PMCOL 525B1/525B2/525B3
Problem Solving Pharmacology & Therapeutics
Winter term, T, R 14:00 - 15:20 / 15:30 - 16:50 /14:00 - 15:20
Coordinator: Dr M Davies

Prerequisites: Consent of Department

Grading: There is no midterm or final examination. Marks are based on the following: a midterm paper based on one of the problems covered in class; a final paper in which the student must construct and solve a therapeutic problem; participation in the group discussions.

This is a course in which graduate students use their knowledge of pharmacology to solve problems in therapeutics. These problems typically focus on identifying the kinds of drugs used to treat certain medical conditions, identifying their mechanisms of action and determining their potential to cause side-effects. Each problem is covered in two sessions: in the first, the students discuss the problem and identify any gaps in knowledge. In the second session, they share their research on the problem and arrive at a consensus on how the problem is best solved.

 

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PMCOL 550

Diabetes and its Pharmacotherapy
Winter Term, M W F 15:00
Coordinator: Dr PE MacDonald

Prerequisites: Consent of Department
Grading: Students will be required to write three papers over the course. Each section students will choose one topic for a 5 page report. The top 2 marks will be taken (and will contribute to 60% of the overall mark). The final exam (40%) will consist of a mixture of short essay questions.

The incidence of diabetes is increasing at an alarming rate in today's society. Understanding diabetes, and present and future treatments, is essential in battling this disease. This course will provide an overview of our current understanding of blood glucose homeostasis; insulin secretion and action; other important blood sugar-regulating hormones; and the pathology of diabetes. Current pharmacological approaches for lowering blood glucose will be discussed; including approaches aimed at replacing insulin, stimulating endogenous insulin production, and increasing insulin action. Finally, the latest experimental approaches, potential drug targets, and current research leading to new pharmacological approaches to the treatment of diabetes will be explored. At the end of the course, students should have an appreciation for the mechanisms that control glucose homeostasis in health and diabetes; the diversity of drug targets and mechanisms by which diabetes drugs promote glucose control, and current rationale and lines of research leading to potential new treatments.

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PMCOL 575
Signal Transduction Systems as Pharmacological Targets
Winter term, M W F 11:00
Coordinator: Dr E Posse de Chaves

Prerequisites: Consent of Department

Grading: Please contact the course coordinator

Do you want to learn about the most advanced therapeutic approaches in development for cancer, neurodegenerative, cardiovascular, autoimmune and other diseases while overcoming the fear of complicated signaling pathways? In this course we analyze the main signaling pathways, their roles in health and disease and the therapeutic approaches targeting them.

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PMCOL 612

Drugs and the Nervous System
Fall term, M, W, F 14:00
Coordinator: Dr S Sipione

Prerequisites: Consent of Department

Grading: The final grade will be based on a midterm and a final examination.

No disease can be cured without knowledge of the underlying cause and molecular mechanisms of pathogenesis. The goal of PMCOL412 is to learn about the molecular basis of disorders of the nervous system, current therapies in use, as well as novel potential treatments that are in clinical trials or at the preclinical experimental stage. Research frontiers in pain and neurodegenerative disorders such as Alzheimer, Parkinson and Huntington's disease, amyotrophic lateral sclerosis, multiple sclerosis and HIV-related neurodegeneration, among others, will be explored. Novel therapeutic targets and the potential treatments of tomorrow will be discussed.

 

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